Table 4.
Performance of the classical and updated Charlson Comorbidity Index in predicting 30-days mortality in Staphylococcus aureus bacteremia
| Models for 30-day mortality | Model 1 | Model 2 | Model 3 | Model 4 |
|---|---|---|---|---|
| Variablesa | ||||
| Age, years | 1.037 (1.011–1.064); 0.006 | 1.035 (1.010–1.062); 0.007 | 1.036 (1.010–1.063); 0.006 | 1.037 (1.011–1.064); 0.005 |
| Origin of SAB: community-acquired | 1.857 (1.002–3.439); 0.049 | 1.790 (0.966–3.319); 0.064 | 1.806 (0.978–3.332); 0.059 | 1.854 (0.998–3.442); 0.051 |
| Foci: pulmonary | 2.112 (1.001–4.454); 0.050 | 2.267 (1.086–4.732); 0.029 | 2.119 (1.007–4.459); 0.048 | 2.072 (0.979–4.387); 0.057 |
| Pitt bacteremia score: ⩾2 points | 3.524 (1.905–6.518); 0.0001 | 3.449 (1.871–6.358); 0.0001 | 3.496 (1.893–6.458); 0.0001 | 3.420 (1.845–6.338); 0.0001 |
| Classical CCI (continuous variable) | 1.103 (0.967–1.257); 0.144 | – | – | – |
| Classical CCI: ⩾3 points | – | 1.082 (0.571–2.051); 0.810 | – | – |
| Updated CCI (continuous variable) | – | – | 1.097 (0.956–1.258); 0.189 | – |
| Updated CCI: ⩾4 points | – | – | – | 1.984 (1.052–3.741); 0.034 |
| Statistics | ||||
| Akaike Information Criterion | 264 | 266 | 264 | 262 |
| Hosmer-Lemeshow testb | 0.263 | 0.052 | 0.773 | 0.300 |
| AUC (95% CI)c | 0.72 (0.65–0.79) | 0.72 (0.65–0.79) | 0.73 (0.66–0.79) | 0.74 (0.67–0.80) |
SAB, Staphylococcus aureus bacteremia. CCI, Charlson comorbidity index. AUC, area under the curve.
a
Data denote Odds ratio (95% confidence interval); P value from Wald test.
b
Data denote P value from Hosmer and Lemeshow goodness of fit test.
c
Data denote the area under the receiver operating characteristic curve (95% confidence interval).