Table 1.

Summary of commissioned rotary mechanical circulatory support systems.

Device	Manufacturer	Flow	Side	Location	Suspension and bearings	Size	Output	Approvals
HeartAssist 5	ReliantHeart	Axial	LV	Intracorporeal	Hydrodynamic (purged)	30(D) × 71(L)	5–10 lpm	FDA (BTT adult) trials, FDA (BTT pediatric), EU (BTT, DT)
HeartMate II	Thoratec	Axial	LV	Intracorporeal	Mechanical (blood immersed)	40(D) × 60(L): 63 mL	3–10 lpm	FDA (BTT, DT), EU (BTT, DT)
INCOR	Berlin Heart	Axial	LV	Intracorporeal	Electromagnetic	30(D) × 114(L)	5 lpm	FDA (BTT) trials, EU (BTT, DT)
Impella	Abiomed	Axial	LV, RV, BV	Transvalvular	Magnetic and hydrodynamic	12 Fr to 21 Fr	2.5–5 lpm	FDA (6 h), EU
HeartWare HVAD	HeartWare	Centrifugal	LV, RV, BV	Intracorporeal	Electromagnetic and hydrodynamic	50 mL	10 lpm	FDA (BTT), FDA (DT) trials, EU (BTT, DT)
HeartMate III	Thoratec	Centrifugal	LV	Intracorporeal	Electromagnetic	69(D) × 30(H): 50 mL	13 lpm	FDA trials, EU
CentriMag	Thoratec	Centrifugal	LV, RV, BV	Extracorporeal	Magnetic	31 mL	9.9 lpm	FDA (6 days LVAD and 30 days RVAD), EU (30 days)
PediMag	Thoratec	Centrifugal	LV, RV, BV	Extracorporeal	Magnetic	14 mL	1.5 lpm	FDA (6 days), EU (30 days)
EvaHeart	EvaHeart	Centrifugal	LV	Intracorporeal	Hydrodynamic (purged)	55(D) × 64(H): 132 mL	12 lpm	FDA (BTT) trials
BPX-80	Medtronic	Centrifugal	LV	Extracorporeal	Mechanical	79(D) × 66(H): 86 mL	10 lpm	FDA (6 h), EU
BP-50	Medtronic	Centrifugal	LV	Extracorporeal	Mechanical	48 mL	1.5 l pm	FDA (6 h), EU
Synergy	HeartWare	Mixed	LV, RV, BV	Intracorporeal	Magnetic and hydrodynamic	12(D) × 49(L): 1.5 mL	0.3–6 lpm	FDA (BTT, BTR) trials, EU (BTT, BTR)

BTD: bridge to decision; BTR: bridge to recovery; BTT: bridge to transplant; DT: destination therapy; VAD: ventricular assistive device; TAH: total artificial heart; FDA: Food and Drug Administration; BV: biventricular; LV: left ventricle; RV: right ventricle.