Table 2.
Summary of other rotary mechanical circulatory support systems.
Device | Manufacturer | Flow | Side | Location | Suspension and bearings | Size | Output | Approvals |
---|---|---|---|---|---|---|---|---|
Jarvik 2000 | Jarvik Heart | Axial | LV | Intracorporeal | Mechanical (blood immersed) | 25(D) × 55(L) | 3–7 lpm | FDA (BTT, DT) trials, EU (BTT, DT) |
DuraHeart | Terumo Heart | Centrifugal | LV | Intracorporeal | Magnetic and hydrodynamic | 72(D) × 45(H): 196 mL | 2–10 lpm | FDA (BTT, DT) trials discontinued, EU (BTT, DT) |
CorAide | Arrow | Centrifugal | LV | Intracorporeal | Magnetic and hydrodynamic | 84 mL | 2–8 lpm | Pre-clinical testing |
DexAide | Cleveland Clinic | Centrifugal | RV | Intracorporeal | Magnetic and hydrodynamic | 69 mL | 2–6 lpm | Pre-clinical testing |
TandemHeart | CardiacAssist | Centrifugal | LV, RV, BV | Extracorporeal | Hydrodynamic (purged) | 10 mL | 4 lpm | FDA trials, Canada (Class 4) |
PediaFlow | PediaFlow Consortium | Mixed | LV, RV, BV | Intracorporeal | Electromagnetic | 28(D) × 51(L) | 0.3–1.5 lpm | In development |
MiFlow | HeartWare | Mixed | LV | Intracorporeal | Electromagnetic | 22 mL | 2–6 lpm | Clinical trials expected |
BTD: bridge to decision; BTR: bridge to recovery; BTT: bridge to transplant; DT: destination therapy; VAD: ventricular assistive device; TAH: total artificial heart; FDA: Food and Drug Administration; BV: biventricular; LV: left ventricle; RV: right ventricle.