Table 3.
Interaction with Smoking Status
| Factor | Case/Ctrl | aOR (95%CI)1 | Interactions (95%CI)1 | |
|---|---|---|---|---|
| Menarche at 17 or later | Ever smoking | |||
| No | No | 275/838 | 1.00(Ref) | |
| No | Yes | 94/170 | 2.36 (1.70, 3.27) | RERI = −0.43 (−1.36, 0.5) |
| Yes | No | 217/620 | 1.28 (1.02, 1.61) | ROR = 0.73 (0.47, 1.14) |
| Yes | Yes | 86/169 | 2.21 (1.56, 3.12) | |
| Menopause at 55 or later | Ever smoking | |||
| No | No | 367/1188 | ||
| No | Yes | 146/308 | 1.98 (1.51, 2.59) | RERI = 0.87 (−1.39, 3.12) |
| Yes | No | 95/185 | 1.60 (1.19, 2.15) | ROR = 1.09 (0.53, 2.25) |
| Yes | Yes | 22/24 | 3.45 (1.80, 6.60) | |
| Parity | Ever smoking | |||
| Parity> = 3 | No | 335/1069 | ||
| Parity> = 3 | Yes | 129/276 | 1.86 (1.40, 2.48) | RERI = 0.96 (−0.39, 2.3) |
| Parity = 0, 1 or 2 | No | 163/395 | 1.32 (1.03, 1.69) | ROR = 1.28 (0.76, 2.15) |
| Parity = 0, 1 or 2 | Yes | 52/68 | 3.13 (2.03, 4.83) | |
| Gravidity | Ever smoking | |||
| Gravidity> = 3 | No | 352/1111 | ||
| Gravidity> = 3 | Yes | 132/290 | 1.77 (1.33, 2.34) | RERI = 1.71 (0.03, 3.38) |
| Gravidity = 0, 1 or 2 | No | 146/353 | 1.26 (0.98, 1.62) | ROR = 1.68 (0.98, 2.89) |
| Gravidity = 0, 1 or 2 | Yes | 49/54 | 3.73 (2.36, 5.90) | |
| #live birth = 0, 1 or 2 | Ever smoking | |||
| No | No | 333/1058 | ||
| No | Yes | 128/273 | 1.85 (1.39, 2.47) | RERI = 0.95 (−0.36, 2.27) |
| Yes | No | 165/406 | 1.30 (1.01, 1.66) | ROR = 1.29 (0.77, 2.16) |
| Yes | Yes | 53/71 | 3.10 (2.02, 4.76) | |
Notation:
Point estimates and 95% confidence intervals were adjusted for age (as a continuous variable), family history of lung cancer (yes or no), income, education, county of residence, and BMI (categorical).