Table 2–
Patient reported outcomes by willingness to receive results by phone
| Agreed to Randomization – Willing to Receive Results by Phone N=819 |
Self-Selected In- Person Disclosure – (e.g. preference for in-person disclosure) N=165 |
||||
|---|---|---|---|---|---|
| Scale | Score Range |
Timepoint | Score (Standard Error) | Score (Standard Error) | P value |
| Knowledge | 6–28 | Post Pre-Test Counseling | 22.78 (0.09) | 22.71 (0.22) | NSS |
| Post Disclosure | 23.16 (0.11) | 22.73 (0.23) | NSS | ||
| Change Score | +0.38 (0.11) | 0.02 (0.25) | NSS | ||
| General Anxiety | 0–21 | Post Pre-Test Counseling | 6.84 (0.13) | 7.56 (0.30) | 0.007 |
| Post Disclosure | 6.72 (0.15) | 7.54 (0.33) | 0.003 | ||
| Change Score | −0.12 (0.12) | −0.02 (0.26) | NSS | ||
| General Depression | 0–21 | Post Pre-Test Counseling | 2.79 (0.10) | 3.41 (0.25) | 0.011 |
| Post Disclosure | 3.06 (0.12) | 3.78 (0.28) | 0.002 | ||
| Change Score | +0.27 (0.11) | +0.37 (0.20) | NSS | ||
| State Anxiety | 20–80 | Post Pre-Test Counseling | 35.07 (0.44) | 37.46 (1.09) | 0.008 |
| Post Disclosure | 35.56 (0.49) | 36.74 (1.13) | NSS | ||
| Change Score | +0.49 (0.41) | −0.71 (0.88) | NSS | ||
| Cancer Worry | 0–70 | Post Pre-Test Counseling | 17.65 (0.48) | 20.19 (1.14) | 0.021 |
| Post Disclosure | 18.80 (0.60) | 21.05 (1.23) | 0.043 | ||
| Change Score | +1.15 (0.50) | +0.86 (0.92) | NSS | ||
| Uncertainty | 0–15 | Post Pre-Test Counseling | 6.54 (0.38) | 7.38 (0.59) | 0.030 |
| Post Disclosure | 8.19 (1.24) | 8.63 (1.25) | NSS | ||
| Change Score | +1.65 (1.36) | +1.25 (1.39) | NSS | ||
| Satisfaction | 9–45 | Post Pre-Test Counseling | 38.39 (0.15) | 38.18 (0.32) | 0.047 |
| Post Disclosure | 37.98 (0.26) | 38.07 (0.50) | NSS | ||
| Change Score | −0.42 (0.26) | −0.11 (0.47) | NSS | ||
| Planning Screening Mammogram | 1–7 | Post Pre-Test Counseling | 5.99 (0.08) | 6.11 (0.13) | NSS |
| Post Disclosure | 5.84 (0.10) | 6.16 (0.12) | NSS | ||
| Change Score | −0.15 (0.12) | 0.05 (0.14) | NSS | ||
| Planning Screening MRI | 1–7 | Post Pre-Test Counseling | 4.13 (0.14) | 3.94 (0.20) | NSS |
| Post Disclosure | 4.08 (0.15) | 4.09 (0.23) | NSS | ||
| Change Score | −0.05 (0.16) | +0.15 (0.23) | NSS | ||
| Planning Prophylactic Mastectomy† | 1–7 | Post Pre-Test Counseling | 3.30 (0.11) | 3.34 (0.18) | NSS |
| Post Disclosure | 2.94 (0.15) | 3.05 (0.21) | NSS | ||
| Change Score | −0.36 (0.17) | −0.29 (0.25) | NSS | ||
| Planning Prophylactic Oophorectomy† | 1–7 | Post Pre-Test Counseling | 3.92 (0.13) | 4.23 (0.20) | NSS |
| Post Disclosure | 3.39 (0.21) | 3.29 (0.26) | NSS | ||
| Change Score | −0.53 (0.23) | −0.94 (0.33) | NSS | ||
| Planning Colonoscopy† | 1–7 | Post Pre-Test Counseling | 3.27 (0.19) | 3.38 (0.27) | NSS |
| Post Disclosure | 3.36 (0.34) | 3.55 (0.39) | NSS | ||
| Change Score | +0.09 (0.37) | +0.17 (0.43) | NSS | ||
NSS = Not Statistically Significant - P =>0.05
All p values included adjustment for baseline differences (age and multi-gene panel testing) between non-randomized groups
Assuming a 20% False Discovery, all statistically significant findings in table 2 would still be statistically significant
†
Only asked in subset of patients when applicable