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. 2019 Apr 8;14(4):e0215106. doi: 10.1371/journal.pone.0215106

Table 1. BG505 SOSIP.664 trimer expression and purification in CHO cells.

Expression conditions PGT145 yield (mg per L) 2G12/SEC yield (mg per L)
Stable expression using CHO-K1 cells with the Flp-In system 3.5–4.3 9.5–10
Transient expression using ExpiCHO-S cells with Expifectamine CHO with Feed and Enhancer 0–0.1 3.0–3.5