Table 1. BG505 SOSIP.664 trimer expression and purification in CHO cells.
Expression conditions | PGT145 yield (mg per L) | 2G12/SEC yield (mg per L) |
---|---|---|
Stable expression using CHO-K1 cells with the Flp-In system | 3.5–4.3 | 9.5–10 |
Transient expression using ExpiCHO-S cells with Expifectamine CHO with Feed and Enhancer | 0–0.1 | 3.0–3.5 |