Table 1. Cairo-Bishop definition of laboratory tumor lysis syndrome .

NOTE: Two or more laboratory changes within three days before or seven days after cytotoxic therapy.

Element	Value	Change from baseline
Uric acid	≥476 micromol/L (8 mg/dL)	25% increase
Potassium	≥6.0 mmol/L (or 6 mEq/L)	25% increase
Phosphorus	≥2.1 mmol/L (6.5 mg/dL) for children or ≥1.45 mmol/L (4.5 mg/dL) for adults	25% increase
Calcium	< 1.75 mmol/L (7mg/ dL)	25% decrease