Table 4.
Diagnostic performance of variables in discriminating benign and malignant SPNs
| Variables | AUC | p | Sensitivity | Specificity | PPV | NPV | Predictive value |
|---|---|---|---|---|---|---|---|
| SPN diameter | 0.690+0.08 | 0.014* | 72.2 | 70.6 | 97.9 | 11.8 | >22.0 |
| LSR0 | 0.615+0.08 | 0.172 | 66.7 | 70.6 | 97.7 | 10 | >0.40 |
| LSR500 | 0.861+0.07 | <0.001* | 100 | 70.6 | 98.5 | 100 | >0.53 |
| LSR1000 | 0.875+0.07 | <0.001* | 88.9 | 88.2 | 99.3 | 29.5 | >0.70 |
| ADC | 0.828+0.07 | <0.001* | 72.2 | 88.2 | 99.1 | 14.3 | ≤0.90 |
| LMR | 0.490+0.08 | 0.908 | 11.1 | 100 | 100 | 5.6 | ≤2.0 |
*
p<0.05 statistical significance
SPN: solitary pulmonary nodule; LSR: lesion spinal cord ratio; ADC: apparent diffusion coefficient; LMR: lesion muscle ratio; AUC: area under curve; NPV: negative predictive value; PPV: positive predictive value