Table 1.
Baseline characteristics of patients with community-acquired pneumonia
| All (n=443) | Survivors (n=399) | Non-survivors (n=44) | P-value | |
|---|---|---|---|---|
| Male | 253 (57.1) | 226 (56.6) | 27 (61.4) | 0.344 |
| Age (yr) | 66.5 ± 15.1 | 66.3 ± 15.2 | 68.6 ± 13.9 | 0.548 |
| Premorbid disease | ||||
| Hypertension | 191 (43.1) | 166 (41.6) | 25 (56.8) | 0.053 |
| Diabetes mellitus | 108 (24.4) | 91 (22.8) | 17 (38.6) | 0.020 |
| Coronary artery disease | 49 (11.1) | 43 (10.8) | 6 (13.6) | 0.566 |
| Congestive heart failure | 6 (1.4) | 6 (1.5) | 0 (0.0) | 0.413 |
| Cerebrovascular accident | 32 (7.2) | 27 (6.8) | 5 (11.4) | 0.264 |
| Pulmonary disease | 45 (10.2) | 42 (10.5) | 3 (6.8) | 0.440 |
| Chronic kidney disease | 35 (7.9) | 32 (8.0) | 3 (6.8) | 0.779 |
| Malignancy | 93 (21.0) | 79 (19.8) | 14 (31.8) | 0.063 |
| Vital sign | ||||
| Systolic blood pressure (mmHg) | 127.8 ± 24.2 | 128.8 ± 23.5 | 118.9 ± 28.4 | 0.010 |
| Diastolic blood pressure (mmHg) | 76.4 ± 16.0 | 76.9 ± 15.3 | 71.3 ± 20.6 | 0.027 |
| Heart rate (beats/min) | 100.3 ± 19.1 | 99.7 ± 18.4 | 106.1 ± 24.0 | 0.034 |
| Respiratory rate (cycles/min) | 20.9 ± 3.8 | 20.7 ± 3.6 | 22.8 ± 4.9 | 0.006 |
| Temperature (°C) | 37.7 ± 0.9 | 37.7 ± 0.9 | 37.6 ± 1.0 | 0.589 |
| Altered mental status | 16 (3.6) | 5 (1.3) | 11 (25.0) | < 0.001 |
| Laboratory results | ||||
| White blood cell (×109/L) | 9.0 (6.5–12.5) | 9.0 (6.5–12.5) | 10.3 (5.4–14.4) | 0.205 |
| Erythrocyte sedimentation rate (mm/hr) | 40.0 (25.0–58.5) | 40.0 (25.0–58.5) | 50.0 (34.0–71.0) | 0.041 |
| C-reactive protein (mg/dL) | 5.1 (2.0–11.1) | 5.1 (2.0–11.1) | 12.0 (7.0–25.1) | < 0.001 |
| Lactate (mmol/L) | 1.2 (0.9–1.6) | 1.2 (0.9–1.6) | 2.3 (1.4–3.2) | < 0.001 |
| pH | 7.44 ± 0.06 | 7.45 ± 0.06 | 7.42 ± 0.08 | 0.021 |
| pO2 (mmHg) | 78.0 ± 55.6 | 78.8 ± 57.6 | 70.3 ± 32.1 | 0.331 |
| SpO2 (%) | 92.8 ± 7.2 | 93.2 ± 6.6 | 88.8 ± 10.7 | 0.010 |
| Hospital course | ||||
| ICU admission | 43 (9.7) | 19 (4.8) | 24 (54.5) | < 0.001 |
| Hospital days | 6.0 (2.0–12.0) | 12.0 (5.5–30.5) | 6.0 (2.0–13.0) | 0.003 |
| Vasopressor use | 49 (11.1) | 22 (5.5) | 27 (61.4) | < 0.001 |
| Mechanical ventilator use | 30 (6.8) | 14 (3.5) | 16 (36.4) | < 0.001 |
Values are presented as number (%), mean±standard deviation, or median (interquartile range).
pH, potential of hydrogen; pO2, partial pressure of oxygen; SpO2, oxygen saturation measured via arterial blood gas analysis; ICU, intensive care unit.