. Author manuscript; available in PMC: 2020 Apr 5.

Published in final edited form as: J Mol Biol. 2019 Mar 13;431(8):1650–1670. doi: 10.1016/j.jmb.2019.03.008

Table 1.

Intrinsic disorder enrichment in multifunctional proteins (MFP) of S. cerevisiae

Dataset	Proteins	Highly disordered proteins	Fraction highly disordered proteins	p^*	Enrichment
Whole proteome	6437	1055	0.16	5e-5	1.44
MFPs	595	137	0.23	5e-5	1.44
Interactome	1622	314	0.19	0.02	1.37
MFPs in interactome	246	64	0.26	0.02	1.37
Hub proteins	530	92	0.17	0.08	1.65
MFP hubs	58	16	0.28	0.08	1.65

MFPs: multifunctional proteins

Highly disordered proteins are those with ≥30% disordered residues

P-values from the two-sample test for equality of proportions (Pearson's chi-squared statistic)