Table 5.
Infectious causes of death following UCBT by time period
| Time Period | P | ||||||
|---|---|---|---|---|---|---|---|
| 1995–2001 | 2002–2007 | 2008–2014 | |||||
| n | % | n | % | n | % | ||
| Bacteria | 18 | 6 | 15 | 5 | 9 | 4 | 0.39 |
| Gram-negative | 9 | 3 | 10 | 3 | 3 | 1 | |
| Gram-positive | 8 | 3 | 3 | 1 | 6 | 3 | |
| Polymicrobial | 1 | <1 | 2 | 1 | 0 | 0 | |
| Fungi | 32 | 11 | 11 | 3 | 6 | 3 | 0.0001 |
| Aspergillus spp. | 23 | 8 | 3 | 1 | 2 | 1 | |
| Candida spp. | 4 | 1 | 7 | 2 | 2 | 1 | |
| Non-Aspergillus molds | 4 | 1 | 1 | <1 | 2 | 1 | |
| Parasites | 3 | 1 | 1 | <1 | 1 | <1 | 0.41 |
| Virusesa | 29 | 10 | 43 | 13 | 21 | 10 | 0.70 |
| Adenovirus | 12 | 4 | 27 | 8 | 11 | 5 | |
| Cytomegalovirus | 7 | 2 | 12 | 4 | 8 | 4 | |
| Herpes simplex | 2 | 1 | 4 | 1 | 0 | 0 | |
| Parainfluenza | 5 | 2 | 6 | 2 | 3 | 1 | |
| Other | 4 | 1 | 0 | 0 | 5 | 2 | |
| Suspected infection, no organism identified | 10 | 3 | 7 | 2 | 7 | 3 | 0.95 |
| Pneumonia | 5 | 2 | 5 | 2 | 3 | 1 | |
| Sepsis | 5 | 2 | 2 | 1 | 4 | 2 | |
UCBT, umbilical cord blood transplantation
Number of deaths may not sum to the deaths from infection in Table 2 because multiple infections were identified for some subjects.
a
Deaths from specific viruses may not sum to category heading because some children had more than one virus identified as a primary cause of death