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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Stress. 2018 Nov 20;22(1):142–150. doi: 10.1080/10253890.2018.1532991

Figure 3.

Figure 3.

F0 NIC and female F1 CUS exposure enhances locomotor sensitization to NIC in female F3, but not F2, offspring. Data (mean ± SEM) represent NIC-induced (1 mg/kg, i.p.) locomotion in (A) F2 male offspring derived from the F1 female lineage, (B) F3 male and female offspring of the F2 male lineage, (C) F2 female offspring derived from the F1 male lineage, and (D) F3 male and female offspring of the F2 female lineage. Significant ‘Time x Lineage’ interaction: **p < 0.01, ***p < 0.001. Sample sizes are reported in parentheses in the figure.