. Author manuscript; available in PMC: 2020 Jan 23.

Published in final edited form as: Chem Rev. 2018 Oct 8;119(2):797–828. doi: 10.1021/acs.chemrev.8b00211

Table 4.

Photosensitizers Approved for Other Therapies.

GENERIC NAME	CHEMICAL NAME	COUNTRY	STRUCTURE	λ_ex (nm) ε_max (M⁻¹ cm⁻¹)	CANCER TYPES
Indocyanine green (ICG)	ICG	USA	Cyanin	800 (N.R.)^a	ICG-guided PDT, medical diagnostic
Verteporfin (BPD-MA)	Visudyne^®	Worldwide	Chlorin	689 (34,000)	Age-related macular degeneration
Topical nanoemulsion of 5-ALA (BF200)	Ameluz^®	USA	Porphyrin precursor	632 (5,000)^b	Mild to moderate actinic keratosis on the face and scalp
Methyl-5-aminolevulinate (MAL)	Metvix^®; Metvixia^®	Worldwide	Porphyrin precursor	635 (N.R.)^a,b	Non-hyperkeratotic actinic keratosis

N.R., not reported.

λ_ex and ε_max refer to PpIX, the porphyrin produced as part of heme biosynthesis.