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. Author manuscript; available in PMC: 2019 Nov 20.
Published in final edited form as: Anal Chem. 2018 Nov 5;90(22):13315–13321. doi: 10.1021/acs.analchem.8b02790

Figure 4.

Figure 4.

Two-dimensional cluster analysis of heterogenous autophagy organelle subpopulations. t-SNE plots from brain tissue show phenotypically identified populations of organelles. Distributions of specific markers on individual organelles were binned into deciles and color-coded according to their assigned decile. Wide variation in color across specific markers in t-SNE plots indicate heterogeneous subpopulations which may have significantly different functions. See Figures S-6 and S-7 for corresponding analysis of liver and skeletal muscle tissue, respectively.