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. 2019 Apr 6;21(5):459–468. doi: 10.1016/j.neo.2019.02.006

Figure 5.

Figure 5

(A) IHC staining detected MSI1 in LGG and GBM patient samples. Scale bars, 100 μm. All data are presented as the mean ± SD, n = 10, *P < .01 by Student's t-test. (B) IHC staining detected ICAM1 in LGG and GBM patient samples. Scale bars, 100 μm. All data are presented as the mean ± SD, n = 10, *P < .01 by Student's t-test. (C) MSI1 and ICAM1 protein co-localization in tissues by IHC staining. Scale bars,100 μm. All data are presented as the mean ± SD, n = 10, *P < .01 by Student's t-test. (D) Different Kaplan–Meier plots of GBM patients with high MSI1 expression, high ICAM1expression, and high MSI1/ICAM1 expression. (E) Schematic illustration depicting that MSI1-mediated mRNA interaction promotes ICAM1 translation and tumor invasion.