Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 8;9:5768. doi: 10.1038/s41598-019-42164-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Overview of the quantitative proteomics analysis. (a) Spectra, peptides and proteins identified from LC/MS-MS proteomics by searching against our S. miltiorrhiza database at critical False Discovery Rates (FDR) of 1%. (b) Principal component analysis (PCA) performed using Markerview. Results represented based on changes in protein regulation. Axes show clear differentiation among samples containing 6 mg g⁻¹ of tanshinones (E2) and 22 mg g⁻¹ of tanshinones (E5) and their respective controls B2 and B5. A different colored circle represents each sample group (ellipses drawn as a guide to the eye). (c) The number of up and down regulated proteins of S. miltiorrhiza at low and high tanshinones concentration obtaining by comparison with their respective control samples. (d) Venn diagram showing the overlap between up- and down-regulated proteins of S. miltiorrhiza at low and high tanshinones concentration.