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. 2019 Apr 8;2:115. doi: 10.1038/s42003-019-0339-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Manhattan plot for the meta-analysis of SUA. The horizontal line represents the genome-wide significance level (α = 5 × 10⁻⁸). Eighteen loci shown in orange were also recently identified by BBJ as being associated with SUA, 10 loci in blue were also identified by other studies and those in red indicate eight novel loci identified in the present study. Blue triangles represent loci containing SNPs with P values of <1 × 10⁻²⁰. SUA serum uric acid, BBJ BioBank Japan