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. 2019 Apr 2;9:216. doi: 10.3389/fonc.2019.00216

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Copyright © 2019 Liu, Zhou, Li, Zhang, Li, Zhou and Song.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enriched pathway statistics and GO functional classification of the DEGs. (A) Scatter plot of enriched pathway statistics. These differentially expressed genes were grouped into gene pathways using the pathway enrichment analysis with the databases of KEGG, BioCyc, Reactome, and Panther. The color and size of the dots represent the range of the p-value and the number of DEGs mapped to the indicated pathways, respectively. Top 20 enriched pathways are shown. (B) Top 20 significantly enriched GO terms. The DEGs are summarized in three main categories: biological process (blue), molecular function (red), and cellular component (yellow). The x-axis indicates -log10 (p-value) and the y-axis indicates different GO terms.