Table 1.
Prenatal, perinatal, and postnatal characteristics of study infants.
| Characteristic | Ureaplasma | p valuea | |
|---|---|---|---|
| Positive infants (n = 40) | Negative infants (n = 63) | ||
| Gestational age (weeks), mean (range) | 26 (23–29) | 26 (22–29) | 0.919 |
| Birth weight (g), mean (range) | 912 (460–1,490) | 872 (440–1485) | 0.394 |
| Sex (male), n (%) | 23 (58%) | 42 (67%) | 0.488 |
| Singleton, n (%) | 31 (78%) | 48 (76%) | >0.999 |
| Antenatal steroids, n (%) | 38 (95%) | 61 (97%) | >0.999 |
| Antenatal antibiotics, n (%) | 27 (68%) | 45 (71%) | 0.889 |
| Antenatal macrolides, n (%) | 21 (53%) | 30 (48%) | 0.416 |
| PPROM > 12 h, n (%) | 13 (33%) | 22 (35%) | >0.999 |
| Histologic chorioamnionitis, n (%)b | 21 (53%) | 28 (44%) | 0.405 |
| Vaginal delivery, n(%) | 20 (50%) | 16 (25%) | 0.023*† |
| Vaginal Ureaplasma, n (%) c | 21 (53%) | 15 (24%) | 0.004**‡ |
| Vaginal GBS, n (%)d | 3 (8%) | 3 (5%) | 0.502 |
| Bacterial vaginosis, n (%)e | 1 (3%) | 2 (3%) | >0.999 |
| Vaginal Candida, n (%) | 13 (33%) | 8 (13%) | 0.020*# |
| Other microbes nasopharyngeally, n (%) | 9 (23%) | 14 (22%) | >0.999 |
| Surfactant administration, n (%) | 27 (68%) | 44 (70%) | 0.731 |
| Ventilation days, mean (range) | 19.1 (0–149) | 20.2 (0–84) | 0.360 |
| Supplemental oxygen days, mean (range) | 14.8 (0–35) | 16.9 (0–60) | 0.677 |
| PDA requiring treatment, n (%) | 9 (23%) | 24 (38%) | 0.201 |
| Presence of central venous line, n (%) | 25 (63%) | 55 (87%) | 0.012*## |
| Central venous line days, mean (range) | 11.2 (2–21) | 12.7 (3–37) | 0.401 |
a
Pearsons's chi-square (X2) and Fisher's exact test for qualitative variables. Q-Q plots, unpaired t and Mann-Whitney U test for quantitative variables.
*
p < 0.05,
**
p < 0.01.
†
Cramér‘s V 0.256 (p 0.014), Cramér‘s V 0.417 (p 0.003),
#
Cramér‘s V 0.241 (p 0.011),
##
Cramér‘s V 0.322 (p 0.01).
b
Histopathological examination performed in 89 placentas.
c
Data available in 89 mothers.
d
Data available in 91 mothers.
e
Nugent score ≥ 7.
GBS, group B Streptococcus; PDA, patent ductus arteriosus; PPROM, preterm premature rupture of membranes.