Table 2.
Bivariate analyses testing for associations between perinatal exposure to Ureaplasma and primary and secondary outcome measures.
| Outcome | Ureaplasma | p valuea | |
|---|---|---|---|
| Positive infants (n = 40) | Negative infants (n = 63) | ||
| BPD totalb | 18/36 (50%) | 32/56 (57%) | 0.218 |
| BPDb | 0.629 | ||
| – Mild | 6/36 (17%) | 12/56 (21%) | |
| – Moderate | 8/36 (22%) | 12/56 (21%) | |
| – Severe | 4/36 (11%) | 8/56 (14%) | |
| RDS ≥ grade 3 | 14 (35%) | 28 (44%) | 0.481 |
| IVH ≥ grade 3 | 11 (28%) | 17 (27%) | 0.949 |
| PVLc | 5/36 (14%) | 10/56 (18%) | 0.487 |
| NEC ≥ stage 2 | 4 (10%) | 9 (14%) | 0.536 |
| ROP ≥ stage 3c | 3/36 (8%) | 7/56 (13%) | 0.478 |
| Late onset sepsis | 10 (25%) | 6 (10%) | 0.060† |
| Meningitis | 0 (0%) | 2 (3%) | 0.288 |
| Death prior to discharge | 4 (10%) | 8 (13%) | 0.602 |
Values are expressed as numbers and proportions.
Pearsons's chi-square (X2), Fisher's exact test and Cramér's V.
Cramér's V 0.211 (p 0.048).
Diagnosis assessed in 92 infants at 36 weeks PMA—based upon the criterion of supplemental oxygen for at least 28 days and classified according to the amount of supplemental oxygen at 36 weeks PMA (11 infants died prior to 28 days of life and prior to 36 weeks PMA).
Data available in 92 infants.
BPD, bronchopulmonary dysplasia; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia; PMA, postmenstrual age; NEC, necrotizing enterocolitis; RDS, respiratory distress syndrome; ROP, retinopathy of prematurity.