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. 2019 Apr 2;13:97. doi: 10.3389/fncel.2019.00097

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Copyright © 2019 Kyle, Wu, Gourzi and Tsirka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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No change in neural stem cell (NSC) or TAC population from PLX5622 treatment. Representative images of the SVZ from 14d of PLX5622 treatment (A), with the dashed line separating the SVZ from the lateral ventricle. DAPI in blue, glial fibrillary acidic protein (GFAP) in green, Sox2 in red, and Ki67 in gray. Quantification of NSC population shown in (B, p = 0.2465), with proliferating (Ki67+) NSCs shown in (C, p = 0.6871). Sox2+ cells, which includes NSCs and TACs, is shown in (D, p = 0.8964). n = 6 for all groups, two sections per n, plotted as per SVZ wall.