Fig. 5.
EpoL treatment decreased oxidative stress in hippocampal organotypic cultures. (A) Epifluorescence images of hippocampal organotypic cultures treated for 4 days with Aβ25-35 (0.5 μM) and co-incubated with EpoL or Epo at neuroprotective concentrations. (B) Images showing the fluorescence intensity of DCF-DA/Hoechst signal in CA1 region. Values are mean ± SEM, n = 5 using one-way ANOVA and Tukey test. ****:p < 0.0001 versus neuronal culture treated with Aβ; ++++:p < 0.001 versus control cells; ###:p < 0.001 versus Epo treatment.