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. 2019 Apr 2;12:75. doi: 10.3389/fnmol.2019.00075

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Copyright © 2019 Tao, Li, Wen, Song, Wei, Du, Yang, Xu and You.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The number of MGE-derived cortical interneurons is greatly reduced in the somatosensory cortex of Lhx6-Cre; Sp8^F/F; Sp9^F/F; Rosa-YFP mice compared with Lhx6-Cre; Rosa-YFP and Lhx6-Cre; Sp9^F/F; Rosa-YFP mice at P30. (A–C) GFP⁺ cells in the somatosensory cortex. (D–F) Quantified data from the above experiments. The density of GFP⁺ cells was significantly reduced in mutants compared with controls. Ctx, cortex; CC, corpus callosum. *P < 0.05; **P < 0.01; ***P < 0.001. Scale bars: 200 μm in (A) for (A–C).