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PV+ cortical interneurons are severely reduced in the Lhx6-Cre; Sp8F/F; Sp9F/F; Rosa-YFP somatosensory cortex. (A–C,G–I) GFP/PV and GFP/SST double-immunostained coronal sections. (D–F,J–L) The density of PV+/GFP+ cells was severely reduced in double mutants compared with single mutants and controls, whereas the density of SST+/GFP+ cells was less affected. *P < 0.05; **P < 0.01; ***P < 0.001. Scale bars: 200 μm in (A) for (A–C,G–I).
