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. 2019 Mar 13;8(4):389–397. doi: 10.1530/EC-19-0026

Table 2.

Item descriptive statistics of 45 patients with (treated) primary aldosteronism (phase III).

Item Question Mean Distribution of responses (n = 45)a
Total (n = 45) Untreated (n = 15) MRA (n = 15) ADX (n = 15) 1 2 3 4
1 Have you had headaches? 1.38 1.53 1.40 1.20 30 13 2 0
2 Have you had muscle weakness? 1.38 1.40 1.60 1.23 33 8 3 1
3 Have you been physically limited? 1.73 2.00 1.87 1.33 24 13 4 4
4 Have you lacked energy? 1.89 2.20 1.93 1.53 17 19 6 3
5 Have you felt restless or agitated? 1.47 1.80 1.40 1.20 30 10 4 1
6 Have you felt physically exhausted? 1.56 1.93 1.53 1.20 27 14 1 3
7 Have you felt mentally exhausted? 1.47 1.67 1.40 1.33 31 10 1 3
8 Have you had to urinate frequently during the day? 1.69 1.87 1.60 1.60 22 15 8 0
9 Have you had to urinate frequently at night? 2.04 2.07 2.27 1.80 11 23 9 2
10 Have you felt overly thirsty? 1.58 1.93 1.47 1.33 28 8 9 0
11 Have you taken large quantities of fluid? 1.56 1.87 1.33 1.47 28 9 8 0
12 Have you woken up for long periods during the night? 1.71 1.53 1.93 1.67 23 14 6 2
13 Have you, as far as you know, snored? 2.09 2.33 1.87 2.07 15 16 9 5
14 Did you feel sleepy during the day? 1.84 2.20 1.67 1.67 16 22 6 2
15 Have you felt tired (not rested) when you woke up? 1.84 2.20 1.80 1.53 20 14 9 2
16 Have you worried about the consequences of your high blood pressure? 1.64 2.07 1.57 1.40 24 15 4 2
17 Have you been worried about the consequences of the elevated levels of aldosterone? 1.76 2.27 1.67 1.33 21 16 6 2
18 Have you worried about your treatment causing future health problems? 1.71 1.87 1.93 1.33 22 15 7 1
19 Have you been worried about the side effects of your treatment? 1.71 2.00 1.80 1.33 23 14 6 2
20 Have you felt frustrated about the number of pills that you are taking? 1.93 2.20 1.87 1.73 22 10 7 6
21 Have you felt impatient? 1.49 1.67 1.60 1.20 29 11 4 1
22 Did you feel irritable? 1.69 2.00 1.67 1.40 22 16 6 1
23 Did you get angry easily? 1.58 1.73 1.60 1.40 25 15 4 1
24b Have you had difficulty in concentrating on things, like reading a newspaper or watching television? 1.36 1.40 1.33 1.33 32 11 1 1
25 Have you had difficulty remembering things? 1.58 1.60 1.60 1.53 23 19 2 1
26 Have you had swelling in your legs or ankles? 1.47 1.80 1.40 1.20 31 9 3 2
27 Have you felt frustrated about a possible delay in the diagnosis of primary aldosteronism? 1.49 2.00 1.33 1.13 31 6 8 0
28 Have you felt worried about the diagnosis? 1.53 2.07 1.33 1.20 28 11 5 1
29 Have you had decreased libido? 1.82 1.93 1.80 1.73 25 8 7 5
30 For men: Did you have difficulty obtaining or maintaining an erection? 1.68
n = 34
1.78
n = 9
2.08
n = 13
1.17
n = 12
22 4 5 3

Patients were untreated, after adrenalectomy (ADX) or on mineralocorticoid receptor antagonists (MRA).

a1 = not at all; 2 = a little; 3 = quite a bit; 4 = very much; bitem deleted based on pre-defined criteria (see text).