Table 2.
Item descriptive statistics of 45 patients with (treated) primary aldosteronism (phase III).
Item | Question | Mean | Distribution of responses (n = 45)a | ||||||
---|---|---|---|---|---|---|---|---|---|
Total (n = 45) | Untreated (n = 15) | MRA (n = 15) | ADX (n = 15) | 1 | 2 | 3 | 4 | ||
1 | Have you had headaches? | 1.38 | 1.53 | 1.40 | 1.20 | 30 | 13 | 2 | 0 |
2 | Have you had muscle weakness? | 1.38 | 1.40 | 1.60 | 1.23 | 33 | 8 | 3 | 1 |
3 | Have you been physically limited? | 1.73 | 2.00 | 1.87 | 1.33 | 24 | 13 | 4 | 4 |
4 | Have you lacked energy? | 1.89 | 2.20 | 1.93 | 1.53 | 17 | 19 | 6 | 3 |
5 | Have you felt restless or agitated? | 1.47 | 1.80 | 1.40 | 1.20 | 30 | 10 | 4 | 1 |
6 | Have you felt physically exhausted? | 1.56 | 1.93 | 1.53 | 1.20 | 27 | 14 | 1 | 3 |
7 | Have you felt mentally exhausted? | 1.47 | 1.67 | 1.40 | 1.33 | 31 | 10 | 1 | 3 |
8 | Have you had to urinate frequently during the day? | 1.69 | 1.87 | 1.60 | 1.60 | 22 | 15 | 8 | 0 |
9 | Have you had to urinate frequently at night? | 2.04 | 2.07 | 2.27 | 1.80 | 11 | 23 | 9 | 2 |
10 | Have you felt overly thirsty? | 1.58 | 1.93 | 1.47 | 1.33 | 28 | 8 | 9 | 0 |
11 | Have you taken large quantities of fluid? | 1.56 | 1.87 | 1.33 | 1.47 | 28 | 9 | 8 | 0 |
12 | Have you woken up for long periods during the night? | 1.71 | 1.53 | 1.93 | 1.67 | 23 | 14 | 6 | 2 |
13 | Have you, as far as you know, snored? | 2.09 | 2.33 | 1.87 | 2.07 | 15 | 16 | 9 | 5 |
14 | Did you feel sleepy during the day? | 1.84 | 2.20 | 1.67 | 1.67 | 16 | 22 | 6 | 2 |
15 | Have you felt tired (not rested) when you woke up? | 1.84 | 2.20 | 1.80 | 1.53 | 20 | 14 | 9 | 2 |
16 | Have you worried about the consequences of your high blood pressure? | 1.64 | 2.07 | 1.57 | 1.40 | 24 | 15 | 4 | 2 |
17 | Have you been worried about the consequences of the elevated levels of aldosterone? | 1.76 | 2.27 | 1.67 | 1.33 | 21 | 16 | 6 | 2 |
18 | Have you worried about your treatment causing future health problems? | 1.71 | 1.87 | 1.93 | 1.33 | 22 | 15 | 7 | 1 |
19 | Have you been worried about the side effects of your treatment? | 1.71 | 2.00 | 1.80 | 1.33 | 23 | 14 | 6 | 2 |
20 | Have you felt frustrated about the number of pills that you are taking? | 1.93 | 2.20 | 1.87 | 1.73 | 22 | 10 | 7 | 6 |
21 | Have you felt impatient? | 1.49 | 1.67 | 1.60 | 1.20 | 29 | 11 | 4 | 1 |
22 | Did you feel irritable? | 1.69 | 2.00 | 1.67 | 1.40 | 22 | 16 | 6 | 1 |
23 | Did you get angry easily? | 1.58 | 1.73 | 1.60 | 1.40 | 25 | 15 | 4 | 1 |
24b | Have you had difficulty in concentrating on things, like reading a newspaper or watching television? | 1.36 | 1.40 | 1.33 | 1.33 | 32 | 11 | 1 | 1 |
25 | Have you had difficulty remembering things? | 1.58 | 1.60 | 1.60 | 1.53 | 23 | 19 | 2 | 1 |
26 | Have you had swelling in your legs or ankles? | 1.47 | 1.80 | 1.40 | 1.20 | 31 | 9 | 3 | 2 |
27 | Have you felt frustrated about a possible delay in the diagnosis of primary aldosteronism? | 1.49 | 2.00 | 1.33 | 1.13 | 31 | 6 | 8 | 0 |
28 | Have you felt worried about the diagnosis? | 1.53 | 2.07 | 1.33 | 1.20 | 28 | 11 | 5 | 1 |
29 | Have you had decreased libido? | 1.82 | 1.93 | 1.80 | 1.73 | 25 | 8 | 7 | 5 |
30 | For men: Did you have difficulty obtaining or maintaining an erection? | 1.68 n = 34 |
1.78 n = 9 |
2.08 n = 13 |
1.17 n = 12 |
22 | 4 | 5 | 3 |
Patients were untreated, after adrenalectomy (ADX) or on mineralocorticoid receptor antagonists (MRA).
a1 = not at all; 2 = a little; 3 = quite a bit; 4 = very much; bitem deleted based on pre-defined criteria (see text).