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. 2018 Oct 9;110(11):1190–1200. doi: 10.1093/jnci/djy161

Table 3.

Moderator effects of baseline values on the exercise intervention effect on outcome measures for the total group or stratified for interventions during and post cancer treatment in case of statistically significant moderator effect of timing

Outcome measure Three-way interaction
Moderator effect in total group
Moderator effect during cancer treatment
Moderator effect post cancer treatment
P* βinteraction (95%CI) P* βinteraction (95%CI) P* βinteraction (95%CI) P* βinteraction (95%CI)
Fatigue .89 0.007 (−0.10 to 0.11) .05 −0.05 (−0.10 to 0.000)
Aerobic fitness .04 −0.11 (−0.22 to −0.004) .002 0.11 (0.04 to 0.18) .95 0.002 (−0.08 to 0.08)
Upper body muscle strength .10 −0.10 (−0.21 to 0.02) 1.00 −0.00 (−0.09 to 0.09) <.001 −0.11 (−0.17 to −0.05)
Lower body muscle strength .05 −0.12 (−0.24 to 0.002) .57 0.02 (−0.06 to 0.10) .01 −0.10 (−0.18 to −0.02)
Quality of life .07 −0.09 (−0.19 to 0.006) .38 −0.03 (−0.11 to 0.04) <.001 −0.13 (−0.19 to −0.06)
Physical function .65 −0.02 (−0.12 to 0.08) .003 −0.07 (−0.12 to −0.03)
*

P values were calculated using a two-sided likelihood ratio test and examining the interaction term of the linear mixed model analyses. Analyses are adjusted for age, sex and cancer type. CI = confidence interval.