Table 1.

Databases of cancer mutations

Database	URL	Statistics	Description
COSMIC	http://cancer.sanger.ac.uk/cosmic	4M coding mutations, 23 489 publications	Curated collection of mutations in cancer includes data from various sources
COSMIC-Cell Lines	http://cancer.sanger.ac.uk/cell_lines	Exome sequences of 1015 cancer cell lines	Filtered variants from extensively used cancer cell lines, including NCI-60 set
COSMIC-WGS	http://cancer.sanger.ac.uk/wgs	28 366 samples	Large-scale cancer sequencing projects; genome-wide screens
TCGA	https://cancergenome.nih.gov	32 cancer types	Publicly available catalog of major cancer-causing genomic alterations
PCDP	https://www.stjude.org/research/ pediatric-cancer-genome-project.html	2813 samples from 17 cancer types	Data from PCGP, TARGET, DKFZ, MAGIC, BROAD, etc.
ICGC	http://icgc.org	16 000+ donors, 70 projects and 21 tumor sites	Catalog of major cancer-causing genomic alterations obtained as result of large international projects
CCLE	https://portals.broadinstitute.org/ccle/home	1074 samples	Compilation of genomic data from human cell lines
Risctox database	http://risctox.istas.net/en/index.asp? idpagina=607	1750 carcinogenic and mutagenic substances	Describes hazardous substances
CBioPortal	http://www.cbioportal.org/	147 cancer studies	Includes cancer samples from TCGA, ICGC and other sources
UCSC Cancer Genomics Browser	http://xena.ucsc.edu/	720 data sets including TCGA and CCLE	Collection of cancer genomics data with interactive tools