Figure 3.

The placements of (A) all the stimulation electrodes in the mPFC and the OFC and (B) the distribution of all the neurons recorded (+3.72, +3.24, −2.92, −3.12, and −3.36; AP distance [mm] to bregma). (C) Electrophysiological recording of an amygdala neuron responsive to mPFC stimulation (left) that showed a decrease in evoked responses with OFC 20 ms prepulse (n/50 = evoked spikes out of 50 trials). Arrows, electrical stimulation artifacts from OFC and mPFC stimulation, respectively. Arrowheads, evoked spikes in amygdala. (D) OFC activation exerted an inhibitory gating on the mPFC–amygdala pathway at all delays tested (relative to BL; *P < 0.05). Abbreviations refer to Figure 1.