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. 2018 Jun 12;108(1):188–200. doi: 10.1093/ajcn/nqy081

Table 1.

Characteristics of participants in 3 populations according to CC and TT genotypes of APOA2 –265T >C1

TT CC
Low-SFA intake High-SFA intake Low-SFA intake High-SFA intake
BPRHS
n = 80 20 20 20 20
 Women, % 50 50 50 50
 Age, y 59.5 ± 6.8 59.6 ± 6.8 59.5 ± 6.7 58.6 ± 7.6
 Drinker, % 30 60 35 60
 Smoker, % 10 25 35 30
 BMI, kg/m2 31.6 ± 5.8 31.2 ± 5.6 29.4 ± 6.0 34.0 ± 5.72
 SFA, g/d 14.0 ± 4.2 33.7 ± 8.62 14.6 ± 5.0 35.1 ± 12.62
 Total energy, kcal 1699 ± 561 3000 ± 6302 1522 ± 416 2932 ± 6912
GOLDN
n = 379 107 165 39 68
 Women, % 77 42 85 40
 Age, y 46.3 ± 16.8 41.5 ± 14.0 43.8 ± 15.8 43.4 ± 12.7
 Drinker, % 47 45 64 54
 Smoker, % 26 26 31 29
 BMI, kg/m2 27.9 ± 5.5 26.8 ± 5.0 27.1 ± 5.4 29.1 ± 5.9
 SFA, g/d 15.3 ± 4.5 38.0 ± 20.82 15.9 ± 4.0 41.1 ± 19.52
 Total energy, kcal 1351 ± 383 2599 ± 14072 1367 ± 402 2884 ± 12082
FHS
n = 243 74 96 34 39
 Women, % 73 56 71 62
 Age, y 65.1 ± 9.3 62.1 ± 8.2 65.4 ± 9.4 64.4 ± 7.7
 Drinker, % 76 72 91 82
 Smoker, % 12 4 6 10
 BMI, kg/m2 25.3 ± 4.2 27.5 ± 5.42 25.4 ± 3.7 26.7 ± 4.5
 SFA, g/d 16.1 ± 4.2 31.6 ± 9.22 15.9 ± 4.3 30.6 ± 7.62
 Total energy, kcal 1532 ± 349 2284 ± 5122 1528 ± 337 2336 ± 5372

1Age, BMI, SFA, total energy are expressed as means ± SDs. APOA2, apolipoprotein A-II; BPRHS, Boston Puerto Rican Health Study; FHS, Framingham Heart Study; GOLDN, Genetics of Lipid Lowering Drugs and Diet Network.

2Significant differences by t test between high- and low-SFA in participants with CC or TT genotype.