SV deletions in the intronic regions of PTEN, PALB2 and RAD51C and qPCR validation. (A–C) SV deletions in the intronic regions of PALB2, PTEN, and RAD51C. At the top of each panel: epigenetic landscape of SV deletion. From top to bottom, RefSeq genes; layered H3K4Me1, H3K4Me3, and H3K27Ac histone modifications; DNase clusters; clustered ChIP-seq binding sites; The signals of different layered histone modifications from the same ENCODE cell line are shown in the same color. (D) qPCR results for the deletion in PTEN. (E) qPCR results for the deletion in RAD51C.