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. 2018 Sep 11;108(3):453–475. doi: 10.1093/ajcn/nqy107

TABLE 3.

Summary of the β estimates (regression coefficients) from the meta-analysis of the association between BMI and telomere length as the outcome and relative telomere length (T/S ratio) as the independent variable1

Pooled sample3
All (total pooled sample)2 “Young” (18–60 y old) “Middle”-aged (61–75 y old) “Old” (>75 y old)
Line Ethnicity n Estimate 95% CI I 2, % n Estimate 95% CI I 2, % n Estimate 95% CI I 2, % n Estimate 95% CI I 2, %
1 Overall 58 −1.58* −2.14, −1.01* 32.7 55 −2.58* −3.92, −1.25* 80.0* 50 −1.08* −1.76, −0.39* 0.0 29 0.20 −1.40, 1.80 0.0
2 White 43 −1.87* −2.44, −1.31* 8.1 40 −2.80* −4.77, −0.82* 84.1* 37 −1.65* −2.45, −0.86* 0.0 21 −0.28 −2.29, 1.73 0.0
3 African American 2 5.66 −6.60, 17.92 80.0* 2 5.21 −5.67, 16.08 68.7 2 0.08 −6.20, 6.36 0.0 1 −0.74 −12.62, 11.14
4 Hispanic 3 2.53 −5.18, 10.25 17.7 3 −0.42 −4.19, 3.34 0.0 3 2.31 −2.35, 6.97 0.0 2 27.29 −40.32, 94.61 77.7*
5 Asian 3 −1.11 −4.23, 2.02 60.4 3 −4.50* −5.75, −3.25* 0.0 2 2.18 −2.90, 7.27 0.0 0
6 Native American 1 −2.64* −3.60, −1.68* 1 −4.14* −5.28, −3.00* 1 2.23 −1.00, 5.46 1 4.68 −2.35, 11.71

1The unit of the estimates and 95% CI of the T/S ratio is 10−3. A random-effects model was used. Statistical heterogeneity was estimated by I2 statistics for each of the meta-analyses. *P < 0.05 or I2 >50%.“n” indicates number of studies. T/S ratio, telomere to single-copy gene ratio.

2Adjusted for age and sex.

3Adjusted for sex.