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Xylosylation of the Notch receptor modulates Notch signaling in a dosage-sensitive manner. (A–D) Graphs show the penetrance of wing margin loss (A and B) and wing vein thickening (C and D) phenotypes of Notch heterozygous animals upon loss of the indicated xylosyltransferases at 25°C (A and C) and 30°C (B and D). Error bars indicate standard deviations of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
