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. 2019 Apr 8;18:47. doi: 10.1186/s12933-019-0853-x

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Network plot of treatment comparisons for heart failure. Direct comparison of treatment is linked with a line, the thickness of which represents the number of trials that assess the comparison. SGLT2i sodium-glucoseco-transporter 2 inhibitors, GLP1ra glucagon-like peptide-1 receptor agonists, DPP4i dipeptidyl peptidase 4 inhibitors, TZD thiazolidinediones, MET metformin, SU sulfonylureas, INS insulin, PLA placebo