Table 1.
AIC and BIC values, computed using gamlss, for a number of non-inflated and inflated distribution models of the null probability density function of the T statistic, along with their (rounded) effective degrees of freedom (DF)
| Non-inflated Model | Inflated Model | |||||
|---|---|---|---|---|---|---|
| Model | AIC | BIC | DF | AIC | BIC | DF |
| Promoter | ||||||
| BE | -486,026 | -485,855 | 17 | -486,229 | -486,041 | 19 |
| GB1 | -488,175 | -487,961 | 22 | -488,408 | -488,181 | 23 |
| logitNO | -487,985 | -487,895 | 9 | -492,544 | -492,384 | 16 |
| logitTF | -493,963 | -493,792 | 18 | -493,944 | -493,762 | 19 |
| logitSST | -494,260 | -494,019 | 25 | -494,242 | -493,992 | 26 |
| Gene body | ||||||
| BE | -482,633 | -482,474 | 17 | -482,608 | -482,440 | 18 |
| GB1 | -484,822 | -484,615 | 27 | -484,798 | -484,581 | 23 |
| logitNO | -490,890 | -490,730 | 17 | -490,872 | -490,702 | 18 |
| logitTF | -495,777 | -495,594 | 19 | -495,751 | -495,560 | 20 |
| logitSST | -498,362 | -498,133 | 24 | -498,337 | -498,099 | 25 |
The results were obtained by fitting each model to T statistic values within promoter regions and gene bodies obtained from all six reference/reference comparisons. Entries in bold highligth the proposed model, which is shown here to produce the best AIC and BIC scores
BE: beta distribution; GB1: generalized beta type 1 distribution; logitNO: logit normal distribution; logitTF: logit t-family distribution; logitSST: logit skewed Student’s t distribution