Figure 7.
Expression of GLUT1 in the hippocampus of APP/PS1 transgenic mice was determined by (a) immunohistochemistry staining and (b) western blotting. (c) The expression of GLUT1 was determined by western blotting. Control (A): C57BL/6J mice; APP (B): APP/PS1 mice; APP + D (C): donepezil; APP + Gh (D): GAPT high dose; APP + Gm (E): GAPT middle dose; APP + Gs (F): GAPT small dose. **P < 0.01 versus control group, △P < 0.05 versus model group, △△P < 0.01 versus model group; ANOVA. The expression of GLUT1 in the donepezil group and each GAPT group were increased (P < 0.01). The expression of GLUT3 in the donepezil group and GAPT middle-dose group were increased (P < 0.01).