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. 2019 Apr 8;19:335. doi: 10.1186/s12885-019-5457-z

Table 3.

Univariable and multivariable analyses of metastatic survival duration in 108 patients

Prognostic factors Univariable analysis Multivariable analysis
HR (95% CI) P-value HR (95% CI) P-value
Age 0.818 0.361
 <60 1.161 (0.575–2.344) 1.328 (0.722–2.442)
 ≥60 1 1
Gender 0.287 0.063
 Male 1.375 (0.545–3.470) 0.511 (0.252–1.036)
 Female 1 1
Primary tumor Grade 0.0028 0.293
 G1 0.502 (0.144–0.756) 0.51 (0.147–1.782)
 G2 1 1
Hepatic Tumor Number 0.000 0.000
 Single 0.17 (0.123–0.214) 0.07 (0.023–0.214)
 Multiple 1 1
Lymph-node meta 0.035 0.374
 Present 1.057 (0.393–2.839) 0.988 (0.371–2.629)
 Absent 1 1
Tumor origin 0.273 0.329
 Pancreas 0.490 (0.139–1.732) 1.463 (0.682–3.138)
 GI tract 1 1
Treatment modality 0.009 0.045
 Local treatment 0.817 (0.690–0.917) 0.801 (0.684–0.887)
 Systemic treatment 0.921 (0.702–0.998) 0.922 (0.781–0.998)
 Combined treatment 1 1
Elevation of ki67 index 0.022 0.027
 Yes 1.997 (1.018–3.547) 1.396 (1.174–3.483)
 No 1 1
Longest hepatic tumor diameter 0.343 0.775
 > 4.5 0.644 (0.2–2.072) 0.875 (0.352–2.175)
 <=4.5 1 1