• Establish the NHS as an internationally recognised centre of research excellence

• Attract, develop and retain the best research professionals to conduct people-based research

• Commission research focused on improving health and social care

• Strengthen and streamline systems for research management and governance

• Increase the opportunities for patients and the public to participate in, and benefit from, research

• Promote and protect the interests of patients and the public in health research

• Drive faster translation of scientific discoveries into tangible benefits for patients

• Maximise the research potential of the NHS to contribute to the economic growth of the country through the life sciences industry

• Act as a sound custodian of public money for the public good