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. 2019 Apr 8;15:108. doi: 10.1186/s12917-019-1836-6

Table 6.

Antimicrobial susceptibility profiles in this study and previous studies of Salmonella isolates from broiler chickens in Japan

Antimicrobial agent MIC break-point (μg/mL) No. of resistant isolates (%)
Previous studies This study
2004–2006
(n = 120)a
2007–2008
(n = 93)b
2009–2012
(n = 243)c
SM ≥16 120 (100) 86 (92.5) 231 (95.1)
OTC ≥16 120 (100) 86 (92.5) 222 (91.4)
SUL ≥512 120 (100) 86 (92.5) 221 (91.0)
AMP ≥32 29 (22.4) 34 (36.5) 134 (55.1)
CTX ≥4 11 (9.1) 33 (35.5) 128 (52.7)
KM ≥64 9 (7.5) 12 (12.9) 16 (6.6)
CFX ≥32 0 (0.0) 8 (8.6) 15 (6.2)
OFLX ≥2 25 (20.8) 11 (11.8) 4 (1.6)
CP ≥32 0 (0.0) 0 (0.0) 0 (0.0)

AMP ampicillin, CTX cefotaxime, CFX cefoxitin, CP chloramphenicol, SM streptomycin, SUL sulfamethoxazole, OTC oxytetracycline, KM kanamycin, OFLX ofloxacin

aCited from [15]

bCited from [14]

cThis study

*Significantly increased from the period of 2004–2006 (p < 0.05)

# Significantly increased from the period of 2007–2008 (p < 0.05)

$Significantly decreased from the period of 2004–2006 (p < 0.05)