Table 2.

Narrative review search strategy

Database		Search terms	Search number	Applied filters
Cochrane Database of Systematic Reviews	Medical condition terms	TX (Osteoarthritis, knee)	1	Human Language filter (English)
	Treatment terms AND safety	Treatments OR Diet therapy[Mesh] OR Drug therapy[Mesh] OR Rehabilitation[Mesh] OR Surgery [Mesh] OR Therapy AND Safety	2
	Medical condition terms AND treatment terms AND safety	1 AND 2	3
Medline	Treatment terms	TX (osteoarthritis OR degenerative arthritis OR degenerative joint disease)	1	Human Language filter (English)
	Treatment terms AND safety	Treatment OR Surgery OR Knee replacement OR TKR OR knee arthroscopy OR Tibial Osteotomy OR NSAIDs OR Opiates OR Paracetamol OR Glucosamine OR Cortisone OR Hyaluronan Gel OR PRP OR Stem Cells OR Exercise Program OR Weight Loss AND Safety	2
	Medical condition terms AND treatment terms AND safety	1 AND 2	3
PubMed	Medical condition terms	“Osteoarthritis, Knee”[Mesh] OR TITLE-ABS-KEY (osteoarthritis OR degenerative arthritis OR degenerative joint disease)	1	Human Language filter (English)
	Treatment terms AND safety	“Osteoarthritis, Knee/diet therapy”[Mesh] OR “Osteoarthritis, Knee/drug therapy”[Mesh] OR “Osteoarthritis, Knee/prevention and control”[Mesh] OR OR “Osteoarthritis, Knee/rehabilitation”[Mesh] OR “Osteoarthritis, Knee/surgery”[Mesh] OR “Osteoarthritis, Knee/therapy”[Mesh] OR TITLE-ABS-KEY (Treatment OR Surgery OR Knee replacement OR TKR OR knee arthroscopy OR NSAIDs OR Paracetamol OR Glucosamine OR Opiates OR Cortisone OR PRP OR Stem Cells OR Hyaluronan Gel OR Exercise Program) AND “Safety” [MeSH]	2
	1 AND 2	1 AND 2	3

Footnote to Supplement 2: TX: All text; MeSH Medical Subject Headings