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. 2017 Apr 6;19(1):118–123. doi: 10.1093/pm/pnx058

Figure 2.

Figure 2

Percent change in circulating concentrations of eCB and related lipids before and after pain testing and exercise in placebo and naltrexone conditions. Postpain % change values refer to the eCB response to pain testing as a percentage change from baseline plasma concentrations. Postexercise % change values refer to the eCB response to exercise as a percentage change from postpain testing plasma concentrations. A) Significant condition × time interaction effect (P < 0.05; denoted +) for AEA. B) Significant condition × time interaction effect (P < 0.05; denoted +) for OEA. C) No significant main effect for time or condition or significant condition × time interaction found for PEA. D) Significant main effect for time (P < 0.05, denoted *) found for 2-AG. E) Significant main effect for time (P < 0.05; denoted *) found for 2-OG. Error bars are ± SEM. 2AG = 2-arachidonoylglycerol; 2OG = 2-oleoylglycerol; AEA = N-arachidonylethanolamine; OEA = oleoylethanolamine; PEA = palmitoylethanolamine.