Table 4.
Proportion of female patients affected by pregnancy-related CVT in described cohorts (with at least 10 cases of pregnancy-related CVT).
Country | Male: Female ratio | Total of female patients/ total cohorta | Pregnancy | Puerperium | Proportion (%)b | ||
---|---|---|---|---|---|---|---|
Karadas et al.143 | Turkey | 2:11 | 43/51 | 8 | 17 | 58 | |
Sidhom et al.65 | Tunisia | 6:13 | 28/41 | 2 | 7 | 32 | |
Souirti et al.145 | Morocco | 4:9 | 18/26 | 0 | 10 | 56 | |
Pai et al.144 | India | 5:3 | 219/573c | 15 | 8 | ||
Uzar et al.146 | Turkey | 1:2 | 31/47c | 6 | 8 | 45 | |
Dentali et al.49 | Italy/ Czech Republic/ USA | 5:14 | 520/706 | 55 | 11 | ||
Kumral et al.147 | Turkey | 4:9 | 152/220 | 34 | 22 | ||
Misra et al.39,d | India | 3:5 | 41/66 | 12 | 29 | ||
Algahtani et al.148 | Saudi Arabia | 6:23 | 73/92 | 17 | 23 | ||
Wasay et al.149 | Asiae | - | 204f | 9 | 40 | 24 | |
Ruiz-Sandoval et al.150 | Mexico | 2:11 | 50/59 | 6 | 21 | 54 | |
Ben Salem-Berrabah et al.151 | Tunisia | 5:21 | 21/26 | 2 | 8 | 48 | |
Martinelli et al.187 | Italy | 7:19 | 106/145 | 14 | 13 | ||
Koopman et al.152 | Netherlands | 3:14 | 65/79 | 12 | 18 | ||
Ferro et al.5 | Multinational | 1:3 | 465/624 | 24 | 53 | 17 | |
Khealani et al.153 | Pakistan/ United Arab Emirates | 7:8 | 58/109c | – | 18 | 31 | |
Wasay et al.154 | USA | 2:3 | 109/182c | 13 | 12 | ||
Sagduyu et al.155d,g | Turkey | 2:5 | 33/46 | 7 | 7 | 42 | |
Stolz et al.93 | Germany | 5:17 | 61/79 | 13 | 21 | ||
Ferro et al.156 | Portugal | 2:5 | 101/142 | 1 | 10 | 11 | |
Preter et al.81 | France | 8:11 | 59/102 | 11 | 19 | ||
Studies distinguishing CVT in pregnancy or puerperium | 65 | 199 | |||||
Total | 1:2h | 2253/3415h | 460 | 25 |
CVT: cerebral venous thrombosis.
Whenever possible only adult patients were considered.
Proportion of pregnancy-related CVT amongst all females included in each cohort. Total is the pooled estimated calculated using a random model of meta-analysis.
Children included (Pai et al.144: minimum age 3 y; Uzar et al.146: minimum age 5 y; Khealani et al.153: minimum age 10 y; Wasay et al.154: minimum age 13 y).
Non-consecutive patient inclusion.
Pakistan, Iran, Singapore, India and Sri Lanka.
Only women at fertile age included.
Only patients with vein thrombosis (cortical or deep system) without sinus thrombosis.
Wasay et al.149 was excluded from the ratio calculation because the study only described women.