Table 1.
Severity Score | Components | Area Under the Receiver Operator Characteristic Curve |
---|---|---|
PSI [10] | Age, Nursing Home, Comorbidities, AMS, Tachypnea, Hypotension, Hypo- or Hyperthermia, Tachycardia, pH <7.35, BUN ≥30, Na <130, Glucose ≥250, Hematocrit <30%, Partial pressure of arterial oxygen <60 mmHg, Pleural Effusion | 30-day Mortality: 0.70–0.89 CAP Complications: 0.58–0.85 |
CURB-65 [11] | Confusion, Urea ≥7 mmol/L, Tachypnea, Hypotension and Age ≥65 | 30-day Mortality: 0.73–0.87 CAP Complications: 0.60–0.78 |
IDSA/ATS 2007 [14] | Minor Criteria: Tachypnea, PaO2/FiO2 ≤250, Multilobar Infiltrates, Confusion, BUN ≥20, WBC ≤4000, Platelets ≤100000, Hypothermia, Hypotension Major Criteria: Invasive Mechanical Ventilation, Need for Vasopressors |
30-day Mortality: 0.63–0.67 CAP Complications: 0.85–0.88 |
SMART-COP [9] | Hypotension, Multilobar Infiltrates, Albumin <3.5 g/dL, Tachypnea, Tachycardia, Confusion, Hypoxemia and Arterial pH <7.35 | 30-day Mortality: Not assessed CAP Complications: 0.83–0.87 |
SCAP [12] | Major Criteria: pH <7.30, Hypotension Minor Criteria: Confusion, Urea >30 mg/dL, Tachypnea, Multilobar Infiltrates, Hypoxemia, Age ≥80 |
30-day Mortality: Not assessed CAP Complications: 0.75–0.83 |
Williams et al [18] (Pediatric) | AgeR,E, SexE, RaceE, ComorbiditiesR, Household smoke exposure, Season, Symptom Duration, Vomiting/feeding refusal, Hypo/HyperthermiaE, TachypneaR,E, TachycardiaR,E, HypotensionR,E, HypoxemiaR,E, AMSR, Chest IndrawingR, Asymmetric breath sounds, Wheezing, White blood cell countE, Infiltrate PatternR, Pleural EffusionR | Death or CAP Complications: 0.78–0.81 |
Araya et al [19] (Pediatric) | Age, Comorbidities, Hypoxemia, Hypotension, Bacteremia, Multilobar/Complicated Pneumonia, Kidney/Liver Failure and Acute Respiratory Distress Syndrome | Death: 0.94 |
Abbreviations: AMS, altered mental status; CAP, community-acquired pneumonia; E, components of electronic health record-based variable model; IDSA/ATS, Infectious Diseases Society of America/Amercan Thoracic Society; PSI, pneumonia severity index; R, components of reduced variable model; SCAP, severe CAP.
aTable adapted from Pereira JM, Paiva JA, Rello J. Assessing severity of patients with community-acquired pneumonia. Semin Respir Crit Care Med. 2012;33:272. CAP complications defined as need for intensive care unit admission, need for mechanical ventilation, or need for vasopressor support.