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. 2019 Apr 2;9:1776. doi: 10.3389/fphys.2018.01776

Table 2.

Joint effect of aging and comorbidities on the outcomes of AP.

Variables Deceased vs. survivors Severe vs. mild AP LOH ≤9 days vs. LOH >9 days

β OR (95% CI) p-value β OR (95% CI) p-value β OR (95% CI) p-value
Age categories
18–34 years (young-aged) NAa NAa 0.961 0 1 (reference) 0 1 (reference)
35–64 years (middle-aged) 0.76 0.76 (0.35–1.67) 0.493 2.00 7.40 (0.99–55.31) 0.051 0.62 1.86 (1.22–2.83) 0.004
>65 years (old-aged) 0 1 (ref) 1.93 6.92 (0.91–52.70) 0.062 0.40 1.50 (0.96–2.33) 0.073
Comorbidity categories
CCI = 0 (none) 0 1 (reference) 0 1 (reference) 0 1 (reference)
CCI = 1 (mild) 0.11 1.12 (0.32–3.90) 0.863 0.04 1.04 (0.52–2.08) 0.911 0.00 1.00 (0.75–1.34) 0.983
CCI = 2 (moderate) 0.09 1.10 (0.26–4.68) 0.900 −0.02 0.98 (0.45–2.24) 0.960 0.30 1.35 (0.95–1.92) 0.092
CCI > 2 (severe) 1.50 4.48 (1.57–12.80) 0.005 0.74 2.10 (1.08–4.09) 0.029 0.15 1.16 (0.83–1.62) 0.387

Red highlights indicate p < 0.05, orange highlights indicate p < 0.10 but ≥0.05. AP, acute pancreatitis; Charlson Comorbidity Index; CI, confidence interval; LOH, length of hospitalization; NA, not applicable; OR, odds ratio. aanalysis is impossible due to zero events.