. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Acta Neuropathol. 2019 Jan 28;137(3):437–454. doi: 10.1007/s00401-019-01959-4

Table 2.

MSA prion propagation in Tg(SNCA) mice.

Patient Sample	Mean cell infection ± SD, fluorescence/cell (10³ A.U.)^*
Patient Sample	Tg(SNCA^+/+)Nbm	Tg(SNCA*A30P^+/+)Nbm	Tg(SNCA*A53T^+/+)Nbm
C2	2.4 ± 1.0	1.6 ± 0.3	1.8 ± 0.8
C3	2.4 ± 1.0	2.0 ± 0.9	2.1 ± 1.0
C14	1.4 ± 0.3	1.9 ± 0.5	3.3 ± 3.5
C16	2.4 ± 1.0	1.9 ± 0.5	2.0 ± 0.6
C17	1.3 ± 0.4	1.7 ± 0.5	2.1 ± 0.4
MSA6	1.9 ± 0.4	3.3 ± 1.8	78 ± 12
MSA13	2.3 ± 0.6	1.8 ± 0.4	39 ± 22
MSA16	1.8 ± 0.3	2.3 ± 1.1	29 ± 26
MSA17	1.6 ± 0.7	1.7 ± 0.5	13 ± 16
MSA18	1.3 ± 0.1	4.0 ± 6.2	9.2 ± 10

Measurements made from five images per well, n = 6 wells. PTA-precipitated samples were diluted in DPBS 1:10 before testing on α-syn140*A53T–YFP cells.