Table 4.
MIC50 and MIC90 for the active compounds against C. auris strains.
| MIC values (mg/L) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CL-10093 | KCTC 17810 | JCM 15448 | CL-10021 | CL-9998 | CL-10030 | CL-10013 | ||||||||
| MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | MIC50 | MIC90 | |
| (-)-MK 801 hydrogen maleate | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Trifluoperazine dihydrochloride | 32 | 64 | 32 | 64 | 16 | 32 | 32 | 64 | 32 | 64 | 32 | 64 | 64 | 64 |
| Suloctidil | 8 | 8 | 8 | 16 | 4 | 4 | 8 | 8 | 8 | 8 | 4 | 8 | 8 | 8 |
| Ciclopirox ethanolamine | 1 | 4 | 0.5 | 2 | 0.5 | 1 | 1 | 4 | 1 | 8 | 1 | 1 | 1 | 1 |
| Ebselen | 4 | 4 | 4 | 4 | 2 | 4 | 4 | 4 | 2 | 4 | 2 | 4 | 4 | 8 |
| Tamoxifen citrate | 16 | 32 | 32 | 64 | 16 | 16 | 32 | 32 | 16 | 32 | 16 | 32 | 16 | 32 |
| Rolipram | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Thiethylperazine dimalate | 64 | 64 | 64 | 64 | 16 | 32 | 32 | 64 | 32 | 64 | 32 | 64 | 64 | 64 |
| Guanadrel sulfate | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Pyrvinium pamoate | 4 | 4 | 2 | 4 | 1 | 2 | 2 | 4 | 2 | 4 | 2 | 4 | 2 | 4 |