Table II.
Feature | European/North American Cohort | Current Cohort | |||||||
---|---|---|---|---|---|---|---|---|---|
Overall | Caucasian | Mixed | Non-Caucasian | ||||||
% | % | p-value | % | p-value | % | p-value | % | p-value | |
LGAa | 53.6% | 65.2% | 0.006** | 60.0% | 0.221 | 79.2% | 0.006** | 71.4% | 0.093 |
Preterm Birth (<37 weeks) | 32.0% | 44.2% | 0.005** | 48.4% | 0.002** | 33.3% | 0.893 | 38.1% | 0.581 |
Polyhydramnios | 30.7% | 25.4% | 0.168 | 27.3% | 0.475 | 9.52% | 0.004** | 33.3% | 0.805 |
Macroglossia | 83.4% | 72.7% | 0.005** | 71.0% | 0.010** | 79.2% | 0.622 | 72.7% | 0.285 |
Ear creases/pits | 51.0% | 70.4% | <0.001*** | 71.1% | <0.001*** | 69.6% | 0.072 | 68.2% | 0.106 |
Facial Nevus Simplex | 51.0% | 49.3% | 0.687 | 52.7% | 0.746 | 47.8% | 0.768 | 36.4% | 0.178 |
Abdominal Wall Defect | 62.3% | 65.5% | 0.435 | 66.7% | 0.377 | 62.5% | 0.984 | 63.6% | 0.900 |
Omphalocele | 37.7% | 20.9% | <0.001*** | 26.9% | 0.021* | 4.17% | <0.001*** | 13.6% | 0.004** |
Umbilical Hernia | 32.5% | 37.7% | 0.213 | 31.5% | 0.841 | 50.0% | 0.107 | 50.0% | 0.124 |
Diastasis Recti | 29.4% | 18.4% | 0.001** | 18.7% | 0.011* | 26.1% | 0.727 | 9.1% | 0.004** |
Organomegaly | 46.2% | 45.3% | 0.825 | 41.9% | 0.409 | 36.4% | 0.359 | 68.2% | 0.042* |
Nephromegaly | 23.8% | 26.9% | 0.427 | 22.8% | 0.825 | 22.7% | 0.908 | 50.0% | 0.034* |
Hepatomegaly | 18.4% | 24.6% | 0.098 | 22.8% | 0.317 | 27.3% | 0.372 | 30.0% | 0.284 |
Splenomegaly | 9.5% | 13.4% | 0.186 | 13.0% | 0.318 | 9.1% | 0.949 | 20.0% | 0.267 |
Hypoglycemia | 47.6% | 64.5% | <0.001*** | 67.4% | <0.001*** | 58.3% | 0.307 | 59.1% | 0.296 |
Lateralized Overgrowth | 40.8% | 82.5% | <0.001*** | 82.4% | <0.001*** | 79.2% | <0.001*** | 86.4% | <0.001*** |
Tumor | 10.3% | 23.4% | <0.001*** | 22.8% | 0.005** | 17.4% | 0.390 | 31.8% | 0.046* |
significant at p < .05
significant at p < .01
significant at p < .001
Large for gestational age (>90%ile)