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. 2019 Apr 5;12:2563–2575. doi: 10.2147/OTT.S190239

Figure 3.

Figure 3

Figure 3

Silencing of PVT1 induces apoptosis and represses epithelial–mesenchymal transition.

Notes: (A) Apoptosis was assayed in 786-O and Caki-1 cells after silencing of PVT1. (B) Caspase-3 activity of 786-O and Caki-1 cells was assayed after silencing of PVT1. (C and D) Total cellular lysates were subjected to the Western blot analysis with the indicated antibodies. The experiments were repeated three times. The data are expressed as mean ± SD. ***P<0.001.

Abbreviation: PVT1, plasmacytoma variant translocation 1.