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. 2019 Apr 5;15:819–829. doi: 10.2147/NDT.S200501

Table 2.

Psychological, clinical, and biochemical parameters in prostate cancer therapy subgroups

Parameter (ref value) Total (n=100) Prostatectomy only (n=77) Prostatectomy and adjuvant treatment (n=23) Cohen’s d p-value
HADS-Anxiety 3.0 (1.0–7.0) 3.0 (1.0–6.0) 5.0 (3.0–9.0) 0.70 0.01
HADS-Depression 3.0 (1.0–6.0) 2.0 (1.0–4.0) 4.0 (2.0–8.0) 0.77 0.027
ICIQ-total 3.0 (0.0–8.0) 2.0 (0.0–7.0) 7.0 (0.0–13.0) 1.1 0.045
IIEF-5 0.0 (0.0–7.0) 0.0 (0.0–8.0) 0.0 (0.0–5.0) 0.61 0.31
PSA-1 (<4.1 ng/mL) 7.5 (5.4–10.6) 7.1 (5.2–9.3) 10.3 (6.4–17.0) 0.8 0.035
PSA-2 (<4.1 ng/mL) 0.003 (0.003–0.037) 0.003 (0.003–0.017) 0.008 (0.003–0.14) 0.09 0.045
Testosterone (1.23–8.92 ng/mL) 4.63 (3.15–6.26) 5.2 (3.49–6.4) 3.56 (2.47–4.5) 0.70 0.001

Notes: Data are shown as the median (25th–75th quartile). Inter-group differences were assessed using the Mann–Whitney U-test. Effect size was measured using the Cohen’s d method. Significant p-values are shown in bold.

Abbreviations: HADS, Hospital Anxiety and Depression Scale; ICIQ, International Consultation on Incontinence Modular Questionnaire; IIEF-5, International Index of Erectile Function; PSA, prostate-specific antigen; Ref value, reference values.