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. 2019 Mar 29;10:285. doi: 10.3389/fphar.2019.00285

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Copyright © 2019 Ren, Ye, Gong, Ren, Ding, Chen, Liu, Lu, Wei, Xu, Zheng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of the combination of alteronol and ADM on protein levels of apoptosis-related molecules in 4T1 cells. (A) The protein levels of Bax and Bcl-2 were measured by western blot. (B) Quantitative analysis of Bax and Bcl-2 protein levels in 4T1 cells after treatment with alteronol and/or ADM. (C) The protein levels of cleaved PARP, cleaved caspase-9, and cleaved caspase-3 were examined by western blot. (D) Quantitative analysis of cleaved PARP, cleaved caspase-9, and cleaved caspase-3 protein levels after the indicated treatments. ^∗P < 0.05, ^∗∗P < 0.01 vs. control group. ^#P < 0.05, ^##P < 0.01 vs. alteronol group. ^&P < 0.05, ^&&P < 0.01 vs. ADM group. All data are expressed as mean ± SD of three independent experiments.