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. 2019 Mar 28;10:601. doi: 10.3389/fimmu.2019.00601

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Copyright © 2019 Morgan, Tseng, Gallais, Leineweber, Buchmann, Riccardi, Nabhan, Lo, Gani, Szely, Zhu, Yang, Kiessling, Vohr, Pallardy, Aswad and Turbica.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of proinflammatory cytokine mRNA in moDC following treatment with native or aggregated infliximab (A) and natalizumab (B). Immature moDC were treated with native or stressed (SSL2 or HSL2) antibodies. Transcripts were measured after 6 h (for IL-1β, IL-6, IL-8, and TNFα) or 24 h (for IL-12p40) using real-time RT-PCR. Results are expressed as fold change over PBS control. The results from 12 independent experiments are shown. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.